Showing posts with label neonatal mortality. Show all posts
Showing posts with label neonatal mortality. Show all posts

Monday, April 7, 2014

MANA Study Part 4: Vaginal Birth After Cesarean



You are reading Part 4 of my MANA study series. Click to view:

MANA Study Part 1: Intrapartum Mortality Rates

MANA Study Part 2: Neonatal Mortality Rates

MANA Study Part 3: Total Mortality Rates

MANA Study Part 4: Vaginal Birth after Cesarean (currently reading)

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April 4, 2017 Update: a new study from the Midwives Alliance of North America (MANA) confirms that attempting a VBAC at home comes with a much higher risk of neonatal death. The study Perspectives on risk: Assessment of risk profiles and outcomes among women planning community birth in the United States looked at planned, midwife-attended births in a home or freestanding birth center. In the study, they use the term LAC (Labor after Cesarean) instead of using the term TOLAC or attempted VBAC.
Rates are as follows for women attempting birth at home or freestanding birth center:
Women with prior vaginal birth, no cesarean history: 1.03/1000
Women attempting VBAC with prior vaginal birth: 1.27/1000
Women attempting VBAC without prior vaginal birth: 10.2/1000

Yes, you read that outrageously awful rate correctly: 10 neonatal deaths per one thousand!

Compare those rates to USA hospitals: 
Hospital CNMs (lower risk pregnancies) = 0.35/1000 to 0.55/1000
Hospital MDs (higher risk pregnancies) = 0.43/1000 to 0.63/1000
Hospital attempted VBACs* = 1.3/1000
Hospital repeat cesarean = 0.5/1000

* The hospital attempted VBAC group includes a higher risk group of women. It includes women with and without prior vaginal birth, with and without higher risk medical conditions and also includes fetal deaths - death of baby in uterus prior to onset of labor from 28 weeks gestation and beyond. Fetal deaths were not included in the home and birth center rates above (meaning, the rates would be higher for the home and birth center births if fetal deaths were included).

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For today's post I am discussing VBAC, HBAC and the MANA study outcomes for HBACs. Let's first lay out the different acronyms:

VBAC -- Vaginal Birth After Cesarean
HBAC -- Home Birth After Cesarean
TOLAC -- Trial Of Labor After Cesarean
ERCD -- Elective Repeat Cesarean Delivery
RCS -- Repeat Cesarean Section

TOLAC refers to all women who have had a previous cesarean section (or more than one) who attempt a vaginal birth. The outcome for TOLAC may be vaginal birth (VBAC) or it may be repeat cesarean section. TOLAC therefore includes outcomes for both.

ERCD refers to all women who decided to forgo an attempt at vaginal birth. ERCD is a bit of a deceiving term. While a cesarean section in this group is labeled as “elective” it also includes women who medically needed cesarean sections for reasons aside from having a previous cesarean section (which would mean it is not actually an elective cesarean section). Because women with chronic illnesses, or other such medical contraindications for TOLAC, are lumped into the ERCD group, the risks of ERCD may be overestimated.


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I'm briefly going to discuss various aspects surrounding VBAC before discussing the startling increased risk for babies born at home to mothers attempting a HBAC.

Sunday, March 16, 2014

MANA Study Part 3: Total Mortality Rates

You are reading Part 3 of my MANA study series. Click to view:

MANA Study Part 1: Intrapartum Mortality Rates

MANA Study Part 2: Neonatal Mortality Rates

MANA Study Part 3: Total Mortality Rates (currently reading)

MANA Study Part 4: Vaginal Birth After Cesarean

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Now it's time to put together what we know and figure out the total mortality rates. This is intrapartum mortality plus neonatal mortality. It's important to look at the total mortality as it really gives more complete picture.

As I have done with the previous two posts, I'm going to compare numbers a few different ways. I'll use the same information I did for intrapartum and neonatal comparisons plus I am adding in one more study, the CPM 2000 study, for total mortality comparisons. I'll explain why when I get there. So here they are again:

1. The MANA study - planned home births with a midwife in the USA, attended mostly by CPMs, LMs and LDMs (Certified Professional Midwives, Licensed Midwives and Licensed Direct-Entry Midwives)

2. The Birth Center study - planned births in select CABC-accredited birth centers with a midwife in the USA, attended mostly by CNMs (Certified Nurse Midwives)

3. The CPM 2000 study - planned home births with a CPM (Certified Professional Midwife)

4. USA hospitals - births in hospitals in the USA


ALL RATES DISCUSSED BELOW EXCLUDE ALL LETHAL ANOMALIES. The exception is the hospital group. Excluded from the hospital group are congenital malformations, deformations and chromosomal abnormalities from the hospital group. This may not include all lethal anomalies, as some may be labeled as something else, like cardiac disease, for example.


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First, let's compare the MANA study to the Birth Center study.

Total Mortality Rates, all risk:

MANA study = 2.06/1000

Birth Center study = 0.87/1000

For every 10,000 babies born at home, 20-21 babies will die. 

For every 10,000 babies born at a CABC accredited birth center, 8-9 babies will die.

As I mentioned previously, a part of this increase is due to the fact that the MANA study has more high risk pregnancies than in the Birth Center study. Let's compare low risk only.

Total Mortality Rates, low risk:

MANA study = 1.62/1000

Birth Center study = 0.87/1000

Why is a home birth two times more likely to end in death of a baby? The birth center studies is freestanding birth centers. These are two studies that look at out-of-hospital birth in the USA... why is there such a big difference?

For every 10,000 babies born at home to low risk mothers, 16-17 babies will die.

For every 10,000 babies born at a CABC accredited birth center, 8-9 babies will die.

What does this comparison show us?
1. It shows the increase risk to babies born out of a hospital to high risk mothers (2.06/1000 compared to .87/1000.... insane)
2. It shows the increase risk to babies born out of a hospital under the care of a non-nurse midwife (1.62/1000 compared to .87/1000... not acceptable)

(as I explained above, majority of the midwives in the MANA study are non-nurse midwives; majority of the midwives in the Birth Center study are nurse midwives)

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Now I will compare the MANA study to the CPM 2000 study. Why am I doing this? Because one of the defenses I have seen many, many times now is that home birth advocates are trying to blame the unlicensed midwives that took part in the MANA study for most or all of the bad outcomes. There are 971 births that were under the care of unlicensed midwives in the MANA study. So I am comparing the MANA study to the CPM 2000 study to see if that may potentially be the issue. Here are the outcomes:

Total Mortality Rates, all risk:

MANA study = 2.06/1000

CPM 2000 study = 2.0/1000



Total Mortality Rates, low risk:

MANA study = 1.62/1000

CPM 2000 study = 1.7/1000

As you can see, the mortality rates are nearly identical. 100% of the outcomes in the CPM 2000 study are Certified Professional Midwives. Are unlicensed midwives solely to blame for the bad outcomes in the MANA study? Or can we compare both the MANA study and the CPM 2000 study to the outcomes of the Birth Center study and conclude out-of-hospital births with non-nurse midwives substantially increase the risk of death for a baby? That's how it looks to me but you are free to interpret it however you'd like.

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Finally, I will compare the MANA study outcomes to hospital outcomes. Since I used two different cohorts for hospital births, I will compare both.

Please note: The hospital CNM group is mostly low risk women; the hospital MD group is low risk and high risk. MD refers not only to OB/GYNs but high risk pregnancy specialists, such as perinatologists and even other medical doctors who may deliver babies, even on rare occasions (such as ER doctors).

This first comparison has the hospital cohort that is a closer match to the MANA study cohort. I defined it in my post regarding neonatal mortality rates.

Total Mortality Rates:

MANA study = 2.06/1000

MANA study, low risk only = 1.62/1000

Hospital CNMs = 0.35/1000 to 0.55/1000

Hospital MDs = 0.43/1000 to 0.63/1000

Even compared to the hospital MD group - which has a higher percentage of high risk pregnancies than the MANA study - the risk is greater for babies born at home. Comparing low risk home birth to mostly low risk hospital birth and it is a risk of death 3-5x higher for babies born at home.


This next comparison has the hospital cohort that is much, much broader which gives MANA the advantage, as the MANA study includes an all-around much lower risk group of women in this comparison.

Total Mortality Rates:

MANA study = 2.06/1000

MANA study, low risk only = 1.62/1000

Hospital CNMs = 0.38/1000 to 0.58/1000

Hospital MDs = 0.52/1000 to 0.72/1000

Comparing all risk home births to all risk hospital births, a baby is 1.5 to 4 times more likely to die at home. Comparing low risk home births to mostly low risk hospital births, a baby is 3 to 4 times more likely to die at home.

Again, these figures give MANA the advantage as it includes a higher risk group of women for the hospital outcomes:

For every 10,000 babies born at home, 20-21 babies will die. 

For every 10,000 babies born at home to low risk mothers, 16-17 babies will die.

For every 10,000 babies born to mostly low risk mothers in a hospital, 3-6 babies will die.

For every 10,000 babies born to women of all risk in a hospital, 5-8 babies will die. 

I am going to make one final comparison, using the most recent figures I just outlined (with the hospital cohort that gives MANA the advantage with the lower risk group of women). I am going to compare hospital CNM outcomes to MANA study outcomes for all risk. I am doing so for three reasons:

1. The hospital CNM numbers are not strictly limited to low risk outcomes, like the MANA study low risk outcomes are. There is no way to completely filter out all high risk pregnancy outcomes from hospital data. While it is unlikely that any breech births or twins births are included in the hospital CNM outcomes, it is possible. Regardless, hospital CNMs care for mostly low risk women, but they do not care for only low risk women.

2. This shows why it is necessary for women to take proper screening measures to ensure a mother is low risk for out of hospital births. If she is high risk she should either switch to a hospital CNM or MD where proper monitoring/care for her high risk pregnancy can continue as it should to ensure the safest outcome for mother and baby. If a mother's low risk status is assumed and not confirmed with the necessary/recommended screening measures, she may actually be high risk but may think she is low risk.

3. If your home birth midwife brushes off your high risk pregnancy and/or refers to it as a "variation of normal," you are taking a big risk and you need to be aware of the odds.

Total Mortality Rates:

MANA study, all risks = 2.06/1000

Hospital CNMs, all risks = 0.38/1000 to 0.58/1000

This means a baby is 3 to 6 times more likely to die at home. That is an additional 15-18 babies per 10,000 that die at home under the care of a midwife that would have lived had they been born in a hospital under the care of a CNM.



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Conclusion: 
There currently are over 30,000 home births every year in the USA. This means, for women who are truly (confirmed) low risk, each year at least 31-41 babies die at home births that would have lived had they been born in a hospital. For high risk women, each year at least 29-34 babies die at home births that would have lived had they been born in a hospital.

The safest place of birth for a baby is in a hospital. For babies born outside of the hospital, it is important that their mothers be low risk (throughout pregnancy and during labor/delivery) and that the attendant be a Certified Nurse Midwife who practices under the guidelines set forth by CABC-accredited birth centers.



References:

1. MANA study: http://onlinelibrary.wiley.com/doi/10.1111/jmwh.12172/full

2. Birth Center study: http://onlinelibrary.wiley.com/doi/10.1111/jmwh.12003/full

3. CPM 2000 study: http://www.bmj.com/content/330/7505/1416

4. USA hospital neonatal mortality rates: http://wonder.cdc.gov/

5. There are two sources I have used for hospital intrapartum mortality rates:

    a. 0.3/1000 is from The World Health Organization:
http://whqlibdoc.who.int/publications/2006/9241563206_eng.pdf
(see Table 7.1 on page 21)

    b. 0.1/1000 to 0.3/1000 is from Judith Rooks:
Here are screen shots of a public, online discussion between Judith Rooks, CNM, MPH and Wendy Gordon, CPM, MPH.



As you can see, Wendy Gordon - one of the authors of the MANA study - did not dispute the rates provided by Judith Rooks. Neither Judith Rooks nor Wendy Gordon commented again after that. Eventually the thread - posted on the public Facebook page of an outspoken home birth advocate (The Feminist Breeder) - was deleted by the page admin.

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MANA Study Part 1: Intrapartum Mortality Rates

MANA Study Part 2: Neonatal Mortality Rates

MANA Study Part 3: Total Mortality Rates

MANA Study Part 4: Vaginal Birth After Cesarean


Friday, March 7, 2014

MANA Study Part 2: Neonatal Mortality Rates

You are reading Part 2 of my MANA study series. Click to view:

MANA Study Part 1: Intrapartum Mortality Rates

MANA Study Part 2: Neonatal Mortality Rates (currently reading)

MANA Study Part 3: Total Mortality Rates

MANA Study Part 4: Vaginal Birth After Cesarean

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Neonatal refers to the newborn period of life, specifically the first month. Neonatal mortality rate refers to the death of a baby any time after live birth and through the first 27 days. If a baby dies prior to labor or prior to birth, the baby will not be included in the neonatal mortality rate. Only babies born alive but die some time in those first full 27 days are included in the neonatal mortality rate.

Neonatal mortality rates can be broken up into early neonatal (death in the first week) and late neonatal (death after the first week but before the 28th day). I will be looking at TOTAL neonatal mortality rates, which is simply early neonatal mortality plus late neonatal mortality.

The overall neonatal mortality rate for the United States is 4/1000 (4 deaths for every 1000 live births -- which is the same neonatal mortality rate as Canada). This rate is includes all gestational ages (including extreme prematurity), all risks, all complications, lethal anomalies, etc. For obvious reasons, this is not the correct comparison to the MANA study neonatal mortality rate.

Just as I did for the comparison of intrapartum mortality rates, I am going to compare the neonatal mortality rates from 3 different data sets:

1. The MANA study - planned home births with a midwife in the USA, attended mostly by CPMs, LMs and LDMs (Certified Professional Midwives, Licensed Midwives and Licensed Direct-Entry Midwives)

2. The Birth Center study - planned births in select CABC-accredited birth centers with a midwife in the USA, attended mostly by CNMs (Certified Nurse Midwives)

3. USA hospitals - births in hospitals in the USA


First, let's look at comparing MANA to the Birth Center study.

Here are the neonatal mortality rates, both rates are excluding anomalies:

MANA study = 0.77/1000

Birth Center study = 0.40/1000

That is an increase risk for babies born at home of just shy of two times. Small yes, but per 10,000 it is an additional 3-4 babies that die at home births during the neonatal period.

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Now, let's compare to hospitals using the CDC Wonder Database. Since it is impossible to get an exact comparison group for hospital births, I will use different hospital groups for the comparison: one that is as close of a match as I can get to the MANA study, and one that is broader. I will define each of them below.

In the first comparison, I will try to match the MANA study as close as possible. So the search results will be based off of the following criteria:

Years 2004-2009 (same as the MANA study)
White Women (92.3% of women in the MANA study were white)
Singles and Twins (small percent were twins in the MANA study, the rest were singletons)
37 Weeks and Above (97.5% of women in the MANA study were 37 weeks and above)
Birth weight of 2500 grams or more (99.2% of babies in the MANA study were 2500 grams & up)
Excluding most lethal anomalies*

*Excluded are congenital malformations, deformations and chromosomal abnormalities from the hospital group. This may not include all lethal anomalies, as some may be labeled as something else, like cardiac disease, for example.

My search includes everything else... all ages (maternal), all education levels, all marital statuses, etc.

2004-2006:

2007-2009:


Neonatal mortality rates for hospitals based on this search criteria are:
Medical Doctor = 0.33/1000
Certified Nurse Midwife = 0.25/1000

Please note: The hospital CNM group is mostly low risk women; the hospital MD group is low risk and high risk. MD refers not only to OB/GYNs but high risk pregnancy specialists, such as perinatologists and even other medical doctors who may deliver babies, even on rare occasions (such as ER doctors).

Comparing this similar hospital group to the MANA study and we have the following for neonatal mortality rates:

MANA study = 0.77/1000

Hospital CNMs = 0.25/1000

Hospital MDs = 0.33/1000

MANA study rate is 3 times greater than the hospital CNM rate and 2 times greater than the hospital MD group. Per 10,000 it is an additional 5-6 babies that die at home births during the neonatal period, compared to the hospital CNM group; compared to the hospital MD group, per 10,000 it is an additional 4-5 babies that die at home births during the neonatal period.

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CDC neonatal mortality data is very accurate, despite what MANA and Citizens for Midwifery have claimed (I will get to that in another post). However, birth certificate data isn't perfect. We are potentially sacrificing the high accuracy the more search criteria we use. So that is why I will do another comparison with hardly any criteria selected.

The rates below are based on the following:

Years 2004-2009
Birth weight of 2500 grams or more
Excluding most lethal anomalies*

*Excluded are congenital malformations, deformations and chromosomal abnormalities from the hospital group. This may not include all lethal anomalies, as some may be labeled as something else, like cardiac disease, for example.

My search includes everything else... all races, all ages (maternal), all gestational ages, all singles and multiples, all education levels, all marital statuses, etc.

2004-2006:

2007-2009:


Neonatal mortality rates for hospitals based on this search criteria are:
Medical Doctor = 0.42/1000
Certified Nurse Midwife = 0.28/1000

Please note: As I stated above, the hospital CNM group is mostly low risk women; the hospital MD group is low risk and high risk. MD refers not only to OB/GYNs but high risk pregnancy specialists, such as perinatologists and even other medical doctors who may deliver babies, even on rare occasions (such as ER doctors).

Comparing this similar hospital group to the MANA study and we have the following for neonatal mortality rates:

MANA study = 0.77/1000

Hospital CNMs = 0.28/1000

Hospital MDs = 0.42/1000

MANA study rate is just shy of 3 times greater than the hospital CNM rate and just shy of 2 times greater than the hospital MD group. Per 10,000 it is an additional 4-5 babies that die at home births during the neonatal period, compared to the hospital CNM group; compared to the hospital MD group, per 10,000 it is an additional 3-4 babies that die at home births during the neonatal period.

Again we are seeing an increase to babies born at home compared to hospitals, even when we are looking at a much higher risk hospital group for comparison.

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At least 5 babies from the MANA study that died during the neonatal period were due to hypoxia or ischemia. This basically means those babies were deprived of oxygen at some point. I cannot help but wonder how many of these 5 cases (and potentially more) were due to lack of proper monitoring during labor, especially during second stage (pushing).

For a look at the intrapartum mortality rates, click here.

Up next, I will put it all together and we can look at the total mortality rates.


References:

1. MANA study: http://onlinelibrary.wiley.com/doi/10.1111/jmwh.12172/full

2. Birth Center study: http://onlinelibrary.wiley.com/doi/10.1111/jmwh.12003/full

3. USA Hospitals: http://wonder.cdc.gov/

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MANA Study Part 1: Intrapartum Mortality Rates

MANA Study Part 2: Neonatal Mortality Rates

MANA Study Part 3: Total Mortality Rates

MANA Study Part 4: Vaginal Birth After Cesarean


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